What's good in small concentrations, but lethal in higher? What's a glaring red flag you're encroaching on a lethal concentration?

Comments

• ThirdWorldOrder@lemm.ee ⁨1⁩ ⁨year⁩ ago

  Just about anything including water or salt

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  • howrar@lemmy.ca ⁨1⁩ ⁨year⁩ ago

    Not just about. Literally everything is lethal at a high enough concentration.

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    • Duranie@lemmy.film ⁨1⁩ ⁨year⁩ ago

      LD50’s are fun!

      en.m.wikipedia.org/wiki/Median_lethal_dose

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    • raspberriesareyummy@lemmy.world ⁨1⁩ ⁨year⁩ ago

      I’d argue gravitational force isn’t lethal. As long as you don’t arrive at whatever is pulling you & the gradient of gravity doesn’t change across your body length. You could be perfectly fine (for a while) orbiting a black hole at enormous speeds (assuming you don’t collide with matter in the accretion disc.

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    • ThirdWorldOrder@lemm.ee ⁨1⁩ ⁨year⁩ ago

      The first part of the question asks what is safe in small amounts

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    • davidgro@lemmy.world ⁨1⁩ ⁨year⁩ ago

      I thought about this a bit and concluded that it only applies to physical materials and forces.

      For example: There certainly are lethal ideas, but most of them are not, and much like bosons they can overlap, so filling a person with multiple copies of the same (benign) thought has a diminishing effect.

      But yeah, anything physical has a lethal concentration.

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• fiat_lux@kbin.social ⁨1⁩ ⁨year⁩ ago

  Panadol / Paracetamol / Tylenol / Acetaminophen / C8H9NO2 is exceptionally easy to overdose on. I've done it accidentally a couple of times. It causes liver damage at even lower overdoses, you really don't want that.

  The maximum dosage is 1g every 4 to 6 hours, maximum total 4g a day. I am no doctor but I strongly recommend 6+ hours between doses (I set a timer) and I try very hard to not get to 3g or above per day. It's even worse that plenty of medications just throw it in to the mix casually.

  Unfortunately as the only first line of defence I have against pain, I cannot avoid it altogether.

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  • ilex@lemmy.world ⁨1⁩ ⁨year⁩ ago

    Huh. That might explain the last two weeks. Dental pains. Lot’s of tylenol. And why I feel much better now.

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    • FaceButt9000@lemmy.world ⁨1⁩ ⁨year⁩ ago

      For dental pain I recommend ibuprofen (advil). Seems to work significantly better than acetaminophen (Tylenol) and seems to be much safer.

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    • Foggyfroggy@lemmy.world ⁨1⁩ ⁨year⁩ ago

      Tylenol can be taken with ibuprofen to increase pain relief. Just don’t overdo it.

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  • AppaYipYip@lemmy.world ⁨1⁩ ⁨year⁩ ago

    I accidentally overdosed on acetaminophen after a surgery once. Doctor forgot to tell me (or I was still high when he told me) he gave me acetaminophen during/after the surgery. I thought I still could take up to 4g that day. A few hours after the surgery, the pain started to kick in so I took some acetaminophen. Ended up vomiting uncontrollably.

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  • TurnItOff_OnAgain@lemmy.world ⁨1⁩ ⁨year⁩ ago

    Can you not use ibuprofen?

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    • fiat_lux@kbin.social ⁨1⁩ ⁨year⁩ ago

      Sadly no, the entire NSAID class are off the table. I'm one of the "lucky" few who gets one of the rare but serious side effects.

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• Agent641@lemmy.world ⁨1⁩ ⁨year⁩ ago

  Weed. A gram will get you high. A woolpack full of it can crush you like a grape if falling from the hay loft.

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  • ilex@lemmy.world ⁨1⁩ ⁨year⁩ ago

    woolpack
    From Middle English wolpak, wullepak, equivalent to wool +‎ pack. 
    A bag of wool, traditionally weighing 240 pounds.
    
    

    TIL, Thx

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  • keeb420@kbin.social ⁨1⁩ ⁨year⁩ ago

    Ol Willie was right

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    • Zeppo@sh.itjust.works ⁨1⁩ ⁨year⁩ ago

      Woolie Nelson

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• AsslessChaps@lemmynsfw.com ⁨1⁩ ⁨year⁩ ago

  According to people I know, I’m only ok in small doses.

  Then they leave.

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  • Hadriscus@lemm.ee ⁨1⁩ ⁨year⁩ ago

    So you’ve never had so far the opportunity to test whether or not you are lethal at higher doses ?

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    • BilboBargains@lemmy.world ⁨1⁩ ⁨year⁩ ago

      I think we have a volunteer

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• Guy_Fieris_Hair@lemmy.world ⁨1⁩ ⁨year⁩ ago

  Took a Hazmat class today and the big thing they drilled into our heads was “Everything is toxic at scale.” So make anything you want and there is an IDLH concentration.

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• bevan@kbin.social ⁨1⁩ ⁨year⁩ ago

  Age

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  • ilex@lemmy.world ⁨1⁩ ⁨year⁩ ago

    I think this is one of those “any amount is bad” things.

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    • Wereduck@lemmy.blahaj.zone ⁨1⁩ ⁨year⁩ ago

      Optimal age to be is blastocyst. It’s just downhill from there.

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• FuglyDuck@lemmy.world ⁨1⁩ ⁨year⁩ ago

  dying is a pretty big red flag, you ask me.

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  • fujiwood@lemmy.world ⁨1⁩ ⁨year⁩ ago

    Okay. Do you think dying is a pretty big red flag?

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    • FuglyDuck@lemmy.world ⁨1⁩ ⁨year⁩ ago

      I guess I did ask for that.

      I also guess you like to tell dad jokes.

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• keeb420@kbin.social ⁨1⁩ ⁨year⁩ ago

  Botulism can kill you, botox can kill your wrinkles.

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  • presbypenguin@reddthat.com ⁨1⁩ ⁨year⁩ ago

    And your migraines!

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• agitated_judge@sh.itjust.works ⁨1⁩ ⁨year⁩ ago

  Everything. Literally everything can be fatal in large enough quantities. Quote from one of my chemistry professors: “there are no lethal substances, only lethal doses”

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  • clockwork_octopus@lemmy.world ⁨1⁩ ⁨year⁩ ago

    Even water can be fatal if you drink too much in one sitting.

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    • rich@feddit.uk ⁨1⁩ ⁨year⁩ ago

      Remember the Wii craze in 2007? There was a radio competition called Hold Your Wee for a Wii in which the contestants had to drink throughout the day without going for a piss. One died.

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  • Sethayy@sh.itjust.works ⁨1⁩ ⁨year⁩ ago

    “The dose makes the poison” -some old dude that like found the pharmaceutical industry

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• scarabic@lemmy.world ⁨1⁩ ⁨year⁩ ago

  It’s been said a lot that light alcohol consumption is actually good for your health, but this is not actually true. It improves some health outcomes but the benefits are outweighed by the risk. There is no safe amount of alcohol consumption.

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  • BilboBargains@lemmy.world ⁨1⁩ ⁨year⁩ ago

    Hilarious how the alcohol lobby scratched around for years looking for a good news story about alcohol and came back with some weak sauce link between red wine and heart disease. Meanwhile, 50% of reported sexual assaults are linked with alcohol. Probably more like 80%. How is alcohol legal and LSD is a schedule 1 substance? There is no lethal dose and has been discovered as a treatment resistant depression and PTSD, OCD, etc. Our drug laws are completely wack.

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    • Corkyskog@sh.itjust.works ⁨1⁩ ⁨year⁩ ago

      The real elephant in the room is alcohol is much more destructive and just as addictive than measurable controlled doses of opoids, and also equally if not more destructive than stimulants like amphetamines and cocaine. It’s basically the worst drug in every metric. If every alcoholic got their drinks replaced with MS Contin and or weed, the strain on the health system would be much less. Not to mention all the other negative externalities related to alcohol intoxication.

      I say all this as someone who drinks. I am going to ensure my child is aware of all the negatives at an early age and be open to discussion about substances. People either like or dislike alcohol, and the people who like it have no self control. It’s a stupid drug, I wish I was never introduced the way I was.

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    • scarabic@lemmy.world ⁨1⁩ ⁨year⁩ ago

      Yep and plenty of folks wanted to believe it.

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  • SnowdenHeroOfOurTime@unilem.org ⁨1⁩ ⁨year⁩ ago

    Did anyone not know this at this point? I’m still gonna drink.

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• skillissuer@discuss.tchncs.de ⁨1⁩ ⁨year⁩ ago

  ionizing radiation, according to some hypothesis, vitamin E, selenium, zinc,

  there’s no single “red flag” everything is different

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• Kolanaki@yiffit.net ⁨1⁩ ⁨year⁩ ago

  Water.

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  • jon@lemdro.id ⁨1⁩ ⁨year⁩ ago

    en.wikipedia.org/wiki/Death_of_Leah_Betts

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  • scarabic@lemmy.world ⁨1⁩ ⁨year⁩ ago

    Yeah this just goes to show how the answer to OP’s question really is “everything.”

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• MxM111@kbin.social ⁨1⁩ ⁨year⁩ ago

  Everything is good in moderation. Even drinking too much water can lead to death.

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• plactagonic@sopuli.xyz ⁨1⁩ ⁨year⁩ ago

  There are lots of things that our body needs in really small doses. But anything above can be lethal.

  Some things needs to be in really specific compounds. Like chrome we need really small dose of Cr3+ but Cr6+ is carcinogenic.

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• Cheriebarie@reddthat.com ⁨1⁩ ⁨year⁩ ago

  My medication. Lithium in small exactly precise doses according to each individual is helpful. But we have to take blood tests to check the toxicity.

  We have to stay hydrated and be really careful if we are sick or vomiting

  A warning signs is shaking (I tests my hands regularly), nausea and outcome is dying. Ha.

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  • t_jpeg@lemmy.world ⁨1⁩ ⁨year⁩ ago

    Bipolar?

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    • Cheriebarie@reddthat.com ⁨1⁩ ⁨year⁩ ago

      Yes

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• Travalanche@lemmy.world ⁨1⁩ ⁨year⁩ ago

  Cocaine. A red flag being your heart beating itself to death inside your chest.

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  • hearthing@lemmy.world ⁨1⁩ ⁨year⁩ ago

    Huh. I kinda thought that was supposed to happen.

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    • ironhydroxide@partizle.com ⁨1⁩ ⁨year⁩ ago

      Definitely better inside your chest than outside it. So I hear.

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• Chickenstalker@lemmy.world ⁨1⁩ ⁨year⁩ ago

  You write like Dr Seuss.

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• Extrasvhx9he@lemmy.today ⁨1⁩ ⁨year⁩ ago

  The human body is pretty weak so anything in high concentrations can probably kill us.

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• T156@lemmy.world ⁨1⁩ ⁨year⁩ ago

  Heartbeats. 60 - 70 is good (you can get away with lower if you’re fit, but anything below 40 is bad), and anything above 180 - 200+ tends to be quite bad for your health.

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  • ilex@lemmy.world ⁨1⁩ ⁨year⁩ ago

    Is there a lethal heartbeat? Google didn’t immediately tell me.

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    • T156@lemmy.world ⁨1⁩ ⁨year⁩ ago

      Yes. Anything above 220 tend to be quite bad for your health, since there’s not enough time for your heart’s chambers to fill at that speed.

      As usual with biology, there’s exceptions to the rule, but for your average human, anything past that means that there’s usually not enough blood coming out to keep you alive at those speeds, and your heart may as well not be beating at all, for all the good it does.

      It’s similar to why Ventricular Fibrillation is bad for you, since it’s a similar problem (but only limited to the two main pumping chambers/ventricles of the heart, rather than including the atria.

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• Chainweasel@lemmy.world ⁨1⁩ ⁨year⁩ ago

  Salt.

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• bigbabypuddingsnatcher@kbin.social ⁨1⁩ ⁨year⁩ ago

  Stupidity

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  • infinipurple@lemm.ee ⁨1⁩ ⁨year⁩ ago

    Some might say it’s not lethal enough given how many absolute morons are still around!

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• Drusas@kbin.social ⁨1⁩ ⁨year⁩ ago

  Vitamin A. Probably others as well.

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• JoBo@feddit.uk ⁨1⁩ ⁨year⁩ ago

  Blood sugar. Vital that you have enough to continue functioning but if it stays too high for too long, it will disable and eventually kill you.

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• CaptainBlagbird@lemmy.world ⁨1⁩ ⁨year⁩ ago

  What’s the LD50 of the internet? 🤔

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  • infinipurple@lemm.ee ⁨1⁩ ⁨year⁩ ago

    I dunno, but I suspect we’ve all surpassed it 😅

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  • n3m37h@sh.itjust.works ⁨1⁩ ⁨year⁩ ago

    Reddit

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• loudWaterEnjoyer@lemmy.dbzer0.com ⁨1⁩ ⁨year⁩ ago

  Elephant steak vs elephant

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• TheLordHumungus@lemmy.world ⁨1⁩ ⁨year⁩ ago

  Nicotine, small doses can be okay, but large doses and it’s really lethal

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  • fubo@lemmy.world ⁨1⁩ ⁨year⁩ ago

    Many plant-based drugs, including nicotine, originated as natural insecticides: the plant uses them to make itself poisonous to insects that would eat it.

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  • JoBo@feddit.uk ⁨1⁩ ⁨year⁩ ago

    But impossible to overdose by voluntary inhalation. Just don’t eat, drink or inject lethal doses and you’ll be fine.

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  • ilex@lemmy.world ⁨1⁩ ⁨year⁩ ago

    I’m not sure bout that. I know they say it, but on many occasions I’ve taken 80+mg orally in a day. Lethal dose is supposed to be 60.

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• ji88aja88a@lemmy.world ⁨1⁩ ⁨year⁩ ago

  Booze… Nurofen

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  • FarraigePlaisteach@kbin.social ⁨1⁩ ⁨year⁩ ago

    Apparently there is no longer a lower limit where alcohol is considered beneficial, at all.

    https://www.who.int/europe/news/item/04-01-2023-no-level-of-alcohol-consumption-is-safe-for-our-health

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    • ji88aja88a@lemmy.world ⁨1⁩ ⁨year⁩ ago

      I was thinking more the “merry” side of good rather than healthy good

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• malloc@lemmy.world ⁨1⁩ ⁨year⁩ ago

  LSD

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  • lonlazarus@lemmy.sdf.org ⁨1⁩ ⁨year⁩ ago

    There is no lethal dose of LSD

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    • Zebov@feddit.ch ⁨1⁩ ⁨year⁩ ago

      I’m sure drowning or inhaling it would be fatal. Or something similar to drinking too much water.

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    • Luke_Fartnocker@lemm.ee ⁨1⁩ ⁨year⁩ ago

      I had a friend that od’d on LSD. His brain swelled up and actually cracked his skull. He was only 20. His sister rushed him to the hospital, but he was brain dead by then.

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