Comment on Why do teeth don't regenerate?

sun_is_ra@sh.itjust.works ⁨3⁩ ⁨weeks⁩ ago

• underwire212@lemm.ee ⁨3⁩ ⁨weeks⁩ ago

  You’re saying we could reactivate the gene and get infinite teeth?? 🫨

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  • bluGill@kbin.run ⁨3⁩ ⁨weeks⁩ ago

    Possible, but it may come with downsides you don't like.

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    • sbv@sh.itjust.works ⁨3⁩ ⁨weeks⁩ ago

      Let me guess, the downside is infinite teeth.

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      • bluGill@kbin.run ⁨3⁩ ⁨weeks⁩ ago

        The downside could be something that nobody has imagined yet. That is the problem with change. I'm not against this, but I demand reasonable study. (but not unreasonable levels - vaccines and GMO have been studied enough to conclude they are generally safe despite people yelling more study needed)

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    • jewbacca117@lemmy.world ⁨3⁩ ⁨weeks⁩ ago

      Imagine teeth grew like our nails and had to be clipped regularly

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      • Pat_Riot@lemmy.today ⁨3⁩ ⁨weeks⁩ ago

        Stop

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      • x4740N@lemm.ee ⁨3⁩ ⁨weeks⁩ ago

        I hate that, please stop

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      • SnipingNinja@slrpnk.net ⁨2⁩ ⁨weeks⁩ ago

        Rodents then?

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    • MeekerThanBeaker@lemmy.world ⁨3⁩ ⁨weeks⁩ ago

      Teething 3.0.

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    • Tanoh@lemmy.world ⁨3⁩ ⁨weeks⁩ ago

      Subscription based teeth?

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      • nicknonya@lemmy.blahaj.zone ⁨3⁩ ⁨weeks⁩ ago

        worse, you have to pay to stop them from growing

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    • Mongostein@lemmy.ca ⁨3⁩ ⁨weeks⁩ ago

      Isn’t this the Street Sharks origin story?

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      • jaybone@lemmy.world ⁨3⁩ ⁨weeks⁩ ago

        Are those the snapping guys in West Side Story?

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    • jaybone@lemmy.world ⁨3⁩ ⁨weeks⁩ ago

      Side effects may include dry mouth, diarrhea, attacking swimmers at the beach. Do not take Teethenall if you are allergic to shellfish.

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      • masquenox@lemmy.world ⁨2⁩ ⁨weeks⁩ ago

        attacking swimmers at the beach

        That I could live with.

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    • whoisearth@lemmy.ca ⁨3⁩ ⁨weeks⁩ ago

      Vagina teeth? That’s my fetish.

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  • themeatbridge@lemmy.world ⁨3⁩ ⁨weeks⁩ ago

    I could be wrong, but I don’t think that’s how the drugs in development work. They cause the existing teeth to produce more enamel or something.

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    • originalucifer@moist.catsweat.com ⁨3⁩ ⁨weeks⁩ ago

      you are wrong. all their tests are on subjects missing teeth, not with reduced enamel. this is literally growing replacement teeth.

      https://newatlas.com/medical/tooth-regrowing-human-trial/

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      • themeatbridge@lemmy.world ⁨3⁩ ⁨weeks⁩ ago

        I stand corrected. Thanks!

        I was thinking of this:

        …washington.edu/trials-begin-on-lozenge-that-rebu…

        But your link is far more exciting.

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      • Rhaedas@fedia.io ⁨2⁩ ⁨weeks⁩ ago

        Hopefully that's what it ends up being, as the idea of growing new teeth has been around in science and media for a long time.

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    • Rhaedas@fedia.io ⁨3⁩ ⁨weeks⁩ ago

      The latest work I've seen reactivates the genes to start growing any existing teeth that had stopped. It's for early development problems in children, not for adults. But of course the media seized on the "regrow teeth" part and ran with it. Unless there's a way to implant new teeth seeds and then get them going, adults are still out of luck.

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      • 5wim@slrpnk.net ⁨3⁩ ⁨weeks⁩ ago

        The trial, which will take place at Kyoto University Hospital from September to August 2025, will treat 30 males aged 30-64 who are missing at least one molar.

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    • Slotos@feddit.nl ⁨3⁩ ⁨weeks⁩ ago

      Teeth cannot produce enamel. Enamel is not a living tissue and it was produced by cells outside of the tooth in a coral-like manner. In order to grow a new tooth, you need it to be fully surrounded by specialized living tissue for the whole growth cycle.

      PS: I honestly expected something like this to come out of bioelectric computation research, but progress seems slower there. Or rather knowledge and techniques in other fields is reaching critical mass, giving us these advances.

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      • themeatbridge@lemmy.world ⁨3⁩ ⁨weeks⁩ ago

        Maybe “grow” isn’t the right word, but I was thinking of these lozenges that made headlines a few years ago.

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  • TheFriar@lemm.ee ⁨2⁩ ⁨weeks⁩ ago

    That sorta makes it sound like a nightmare

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• TheRealKuni@lemmy.world ⁨2⁩ ⁨weeks⁩ ago

  though a drug is being developed that could allow us to regenerate teeth

  I think the last time I was this excited about medical science was the COVID vaccine. How I would love to replace my root canal crowns with real teeth!

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