Comment on Grapefruit Redbull

Kolanaki@pawb.social ⁨1⁩ ⁨day⁩ ago

• Donkter@lemmy.world ⁨8⁩ ⁨hours⁩ ago

  Lots of answers but I think the explicit joke here is that grapefruit doesn’t work with certain types of antidepressant medications, which redbull’s clients are presumably on.

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  • Drusas@fedia.io ⁨5⁩ ⁨hours⁩ ago

    I thought it was the "girl" part since most women of reproductive age are on hormonal contraceptives.

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• INeedANewUserName@piefed.social ⁨22⁩ ⁨hours⁩ ago

  Grapefruit disrupts metabolism by Cytochrome P450 enzymes in the liver. They are widely involved in drug metabolism. https://en.wikipedia.org/wiki/Cytochrome_P450

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• A_Union_of_Kobolds@lemmy.world ⁨23⁩ ⁨hours⁩ ago

  Doesn’t it interact with… I can’t remember if it was ecstasy or some normal medicine

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  • Kolanaki@pawb.social ⁨23⁩ ⁨hours⁩ ago

    Only thing that came to mind was diabetics can’t usually have grapefruit. Is the joke that redbull enjoyers are diabetic? 🤔

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    • GreenDust@lemmings.world ⁨23⁩ ⁨hours⁩ ago

      Antidepressants, anxiolytics, stimulants, etc.

      en.wikipedia.org/…/Grapefruit-drug_interactions

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      • Postmortal_Pop@lemmy.world ⁨22⁩ ⁨hours⁩ ago

        And some birth control.

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      • tyler@programming.dev ⁨18⁩ ⁨hours⁩ ago

        I mean that lists off acetaminophen… and it says all citrus juices can do it, so don’t drink juice at all then?

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  • LORDSMEGMA@sh.itjust.works ⁨22⁩ ⁨hours⁩ ago

    Def drink grapefruit juice if you’re taking e. The extra vitamins help a ton and it’ll extend the high.

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    • sad_detective_man@sopuli.xyz ⁨8⁩ ⁨minutes⁩ ago

      Also reduces the toxicity from the metabolites your body makes while processing it. Pretty convenient with all the other good ways they interact

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