Comment on Anon goes on a diet

GissaMittJobb@lemmy.ml ⁨3⁩ ⁨days⁩ ago

Yep, that’s leptin resistance for you. Obesity is really a hormonal condition, and this is why GLP-1 inhibitors are so effective - they actually treat the hormonal condition and allow the recipient to manage their food intake without having their body hormonally work against them.

A layman’s explanation of my best understanding of the subject:

Hunger is controlled by 2 hormones:

As fat cells accumulate, leptin levels also increase, but a person that has developed leptin resistance will not feel the appropriate amount of hunger suppression from the leptin, leading to chronic hunger unless large energy intake is sustained.

source
Sort:hotnewtop