N0t_5ure
@N0t_5ure@lemmy.world
- Comment on Impending toilet paper shortage 2 weeks ago:
SO glad I use a bidet!
- Comment on Impending toilet paper shortage 2 weeks ago:
Just the news of a potential toilet paper shortage will cause a run on toilet paper, as people stock up and hoard it. Did we learn nothing from the pandemic?
- Comment on This homeless character, who doesn't go to the gym and survives on junk food, somehow weights 300lbs of pure muscle 2 weeks ago:
I’m in the U.S., and the medical system is abysmal. Primary care physicians are basically robots that dole out pills based on the “standard of care”, which is a standard produced with health insurer input. I had metabolic syndrome, and uncontrolled high blood pressure despite being on 3 meds. No doctor ever mentioned metabolic syndrome to me, and I figured out that chronic stress was driving my high blood pressure, and presented evidence of this to a cardiologist and told him I needed a beta blocker. That wasn’t next on the list, so he prescribed something else that was worthless, so I had to wait another month to show him the drug did nothing. In the mean time, I found I was able to use exercise to bring down my blood pressure. I did hire a personal trainer, but they were worthless (YMMV on this, as I know others that have had very good trainers).
What got me on the right path was studying longevity science, and deploying the strategy outlined by Peter Attia in his book “Outlive”, which is a free audiobook on spotify premium. Basically, the levers you have to pull are sleep, exercise, nutrition, supplements and drugs. With respect to exercise, he emphasizes resistance training (min 3 hrs per week), zone 2 cardio (6 hrs per week) and HIIT (1 hr per wee).
I had never done resistance training before in my life, and I started with bodyweight fitness in my apartment, which I did for about a year before it became clear that I needed to figure out weight training. I found Joe Delaney’s youtube channel, and thought it would be a good starting point, and I hired a personal trainer, who disregarded my opinion and had me do other things, and gave me a program that was difficult, time consuming, and had significant potential for injury. After a couple of weeks of struggling with that, I tossed it, and did Delaney’s beginner program. After two months of that, I modified it to add exercises to target my specific areas of weakness. It was a good starting point.
With respect to the drugs, I knew it would be difficult to add muscle at my age, so I dug into PEDs. There is a lot of “noise” in this area, but one of the social media influencers I stumbled across referenced Llewellyn’s Anabolics, which provides a thorough summary of pretty much every anabolic compound in common use today, including reference to the actual studies, the common side effects, the effectiveness, etc. Ligandrol is currently in phase 3 clinical trials, but is widely available through grey market sellers on the internet. Thus, there is not only the risk of using a non-FDA approved drug, but also the risk of whether the producer is actually selling you the actual drug. The drug itself had enough human trial data for me to be comfortable with it (note: some SARMs available were abandoned because of major issues, such as causing cancer in rats), and the seller has been around for a while and had a big enough user base that I could be comfortable that I was getting a reasonably good quality drug.
I’ve made some mistakes along the way. For example, I crashed out my testosterone the first time I tried Ligandrol, because I used Nolvadex, a SERM, to maintain testosterone production when on cycle, and it wasn’t up to the task for me.
Overall though, my efforts have been very successful. We have a world of information at our fingertips, so long as we are able to filter out the bullshit. There is a lot of “tribal knowledge” passed from peer to peer, much of which is complete crap, but you can find smart people that review and reference the actual science that can point you in the right direction.
- Comment on This homeless character, who doesn't go to the gym and survives on junk food, somehow weights 300lbs of pure muscle 2 weeks ago:
“Come with me if you want to live.” Image
- Comment on This homeless character, who doesn't go to the gym and survives on junk food, somehow weights 300lbs of pure muscle 2 weeks ago:
To his credit, he is one of the few in Hollywood open to admitting that he uses exogenous anabolics. I’d guess that pretty much all of the older, completely jacked stars are also using such compounds, as it is very difficult to add muscle mass later in life. This creates a very unrealistic body image for the rest of us to live up to.
FWIW, I’m 60 and have been on a health journey over the last several years, and have transitioned from morbidly obese to the best shape of my life. Per my last Dexa scan, my muscle mass, bone density, and body fat percentage are in the top 15% for 30-35 year old men, and I am still progressing. I do, however, cycle with Ligandrol, a SARM, and use HCG combat suppression when on cycle and maintain my endogenous testosterone production. As a consequence, I’ve been able to add a significant amount of muscle mass and improve my health, as muscle is a critical metabolic sink and is also an endocrine organ.
I’ve used the drugs to rehabilitate my body and build a fit, athletic physique that is easily maintained in the gym, even when off cycle. In my opinion (I’m not a doctor and this isn’t medical advice), it is far better for me to use the drugs in a reasonable way to get the functional muscle mass and bone density now, rather than to fight sarcopenia and struggle for years with little progress. I’m in the gym 5 hours a week for resistance training, and stack on average 9hrs per week of cardio on top, with about an hour of that being HIIT.
- Comment on Why don't people wear underwear under the padded bike shorts? 4 weeks ago:
I do.
- Comment on Delicious 1 month ago:
Made by Sean Connery.
- Comment on Can anyone confirm? 1 month ago:
I had Miami and SF on my list, but the others make sense.
- Comment on Musk: Many British people are living in lovely small towns. They are just like Hobbits. Until one day, people show up and start raping their kids 1 month ago:
Sounds like a threat from someone in the Epstein files…
- Comment on Behold, the future! 1 month ago:
Closer view.Image
- Comment on 1978 High School 2 months ago:
She’s smiling because she knows she can afford to buy a house and later chastise her children for being lazy, avocado toast eating renters lacking bootstraps.
- Comment on Y'all remember the Bloodhound Gang? 2 months ago:
Notwithstanding your dipshit teenager neighbor, the song is witty and has a good beat.
- Comment on However you say it, youre wrong. 3 months ago:
Just to be clear, it’s Commander Data, not Commander Data.
- Comment on WHARRGARBL 3 months ago:
That is a different wharrgarbl meme than I’m used to seeing…
- Comment on Marriage 3 months ago:
100%
- Comment on [deleted] 3 months ago:
There is a girl I know who is super cute, and she has resting smiley face. Her demeanor always struck me as odd, until I learned she’s a kindergarten teacher, and then it made sense. She talks to people in the same way she talks to kindergartners.
- Comment on It's a real bargain when you realize it'll fit 6-8 3 months ago:
I just want to say 10 out of 10 title, OP. It took me a minute, but I finally got it!
- Comment on It's a real bargain when you realize it'll fit 6-8 3 months ago:
It’s your mom’s vibrator case.
- Comment on Batteries 4 months ago:
I think it’s more accurate to describe rapamycin as an an immunomodulator, and if you look at the data it paints a pretty compelling picture.
- Comment on Batteries 4 months ago:
I will say that you don’t have to lie down and take it. Over the past few years I’ve been on a journey to restore and rejuvenate my body, and the results have been miraculous. I went from morbidly obese with metabolic syndrome, including uncontrolled high blood pressure, to literally the best physical condition of my life. 60 year old me could kick 30 year old me’s ass any day of the week. All of my health issues have been resolved, and all of my old man aches and pains have gone away. I did a deep dive on the state of the art of longevity science, which is reasonably summarized in Peter Attia’s book Outlive. (It’s a free audiobook on spotify premium.) I’ve basically optimized sleep, exercise, nutrition, supplements, and the use of prescription drugs, including the drug rapamycin. Rapamycin has extended lifespan of every organism it’s been tested in, including budding yeast, fruit flies, mice, rats, and non-human primates. While there are ethical and time considerations that make such placebo controlled lifespan studies in humans difficult, there is data to suggest that rapamycin has a similar therapeutic effect in humans. Joan Mannick’s 2014 study using Everolimus, a slightly tweaked analog of rapamycin, demonstrated that pulsed mTOR suppression in elderly humans greatly ameliorated immunosenescence, the decline in immune function during aging, and the ongoing trials of rapamycin with respect to ovarian aging have shown impressive effects. I’ve been on rapamycin for almost 3 years now, and while I can’t isolate its effects from my other interventions, I’m pretty much never sick and I’ve had significant grey hair reversal, which was unexpected. TLDR: there is a lot you can to mitigate the effects of aging and implement “graceful degradation” in your life.
- Comment on Batteries 4 months ago:
I turn 60 in June. I’m doing this with my body.
- Comment on Are there any good protest songs from the past few years? 4 months ago:
No$hu Fuck ICE ICE Baby
- Comment on How come they don't make generic drugs for cats and dogs. I love my sisters buddy to death. Its just weird that all my meds are generic but animals are name brand. I just hate spend 250 every 3 mon. 4 months ago:
They do. However, the drugs your pet needs may not be off patent, and thus you have to buy branded.
- Comment on the simulation jumped the shark with the is Trump guy 4 months ago:
Jesus, I thought for sure this one was fake. Nope.
- Comment on Let's say hypothetically I wanted to leave the US permanently; 4 months ago:
Children’s television programming geared towards young children (e.g., Bluey, Peppa Pig, etc.) can fill this gap, and are widely used as comprehensible input content by adult language learners.
- Comment on Let's say hypothetically I wanted to leave the US permanently; 4 months ago:
Picking up a new language is much easier if you use the Comprehensible Input method, which is fun and easy. It’s essentially learning language like a child learns. You watch videos that are 100% in the target language. In the beginning, they are super easy, with lots of props, gestures, and other context that helps convey the meaning of the words. As you pick up more and more, you watch more difficult videos. It’s amazing how fast you pick up the new language. In about 3 months I learned enough Spanish to give me around 80%+ comprehension of normal conversation, and better comprehension if the person spoke slowly and clearly. Don’t count out learning a new language, as it is a lot easier than you might think if your only experience is with traditional methods.
- Comment on How sad is that Persian cuisine? 4 months ago:
Okay, I’m going to have to actually stop in and eat there one of these days.
- Comment on How sad is that Persian cuisine? 5 months ago:
Just for the night.
- Submitted 5 months ago to [deleted] | 7 comments
- Comment on Ups and downs 5 months ago:
Joke’s on her, I’m into it.
