Submitted 9 months ago by andrewta@lemmy.world to [deleted]
I know the ng means nanogram
But I’m curious how would I say the above line of 2.1 ng/kg
For context I got it from this paragraph
a lethal dose of 1.3–2.1 ng/kg in humans
Would it be
2.1 nanogram per kilogram?
Also if I wanted to write that as a decimal number how would i write that?
You can say "nanograms per kilogram." You could shorten it to "nanograms per kilo."
If it were mg/kg, you could say "migs per kig." You won't trick me into saying the equivalent for nanograms, though.
What’s wrong with nags? Isn’t that a term for a rundown horse or something?
2.1 ppt (parts per trillion)
That assumes that the particles are the same mass for the drug and human.
You could say a small percent mass.
Yeah it’s typically not used for dosages, rather it’s for concentrations in solution. However strictly speaking the grams cancel in the units of ng/kg and you are left with ppt. I think of ppm and ppt as very small percentages anyway. As per cent means part per one hundred. Can’t use “permille” because it means part per thousand but sounds like part per million.
In the case of a lethal dose, I think it would be fine to say, “it’s lethal at a rate of 2 trillionths of body mass”.
Seriously?
Damn!
Lots of good responses so far.
0.0000000021g/kg
or 0.0000000000021kg/kg, if you wanted the same units both sides…
( I’m presuming this was your last-line’s request )
Fentanyl?
Hell yeah. I know that one. Hold on, I’m gonna inject a very small portion of that into my face. Now you know I’m happy.
RightHandOfIkaros@lemmy.world 9 months ago
“A lethal dose of one point three to two point one (or one and three tenths to two and one tenth) nanograms per kilogram in humans.”
andrewta@lemmy.world 9 months ago
So are they saying nanograms of the stuff per kilograms of the human?
In other words are they saying it’s a ratio compared to the weight of the person?
ZapBeebz_@lemmy.world 9 months ago
That is correct. The ratio is nanograms of substance to kilograms of bodyweight
Ephera@lemmy.ml 9 months ago
Yeah, personally I would say that it’s per kg bodyweight.
But I would also do my darndest to try write it, since “ng/kg” is kind of just nonsense. It makes it look like you could divide the grams out of that to get a fixed ratio, which is not correct at all.
RegalPotoo@lemmy.world 9 months ago
Yeah - the dose is the poison (if you drink enough water it becomes toxic), so if you are talking precisely you need to describe the concentration of a substance in which it is likely lethal to a person, and that’s typically expressed as mass of a substance per mass of bodyweight. A lot of the time you will also see this expressed as an “LD50” value; the dose at which you’d expect 50% of people to die. This accounts for the fact that people’s metabolisms vary quite widely.
~1ng/kg ~= 0.08ug for a typical (~80kg) person, which is a very tiny amount - whatever you are talking about is incredibly toxic.