Thatâs not really how trials for treatments like this work. The non-experimental groups would get standard of care/a comparator which would be used to determine efficacy. It would be unethical to give sugar pills to patients with advanced NSCLC.
Comment on Cuba Libre đ¨đş
Depress_Mode@lemmy.world â¨2⊠â¨weeks⊠ago
Man, imagine slowly dying of late-stage lung cancer, then getting picked to be in a trial for a drug that could greatly improve your situation, but you get put in the control group. Placebos will still cure cancer if you think they will, right?
awfulawful@lemmy.blahaj.zone â¨2⊠â¨weeks⊠ago
terranoid@lemmy.cafe â¨2⊠â¨weeks⊠ago
Placebo knee surgery literally works
somethingsnappy@lemmy.world â¨2⊠â¨weeks⊠ago
That would be because we now know many cartilage related knee surgeries do not.
terranoid@lemmy.cafe â¨2⊠â¨weeks⊠ago
the effect is extremely real though, same with nocebo. They did a study a while ago, told people something was poison oak when it wasnât and rubbed them with it. They broke out in rashes.
somethingsnappy@lemmy.world â¨2⊠â¨weeks⊠ago
Also, worked 30+ years in science and specifically a lot of immunology.
somethingsnappy@lemmy.world â¨2⊠â¨weeks⊠ago
Iâm not going to spend much time reading a LLM generated article from a source that pays people for surveys. In general, you are not wrong as far as placebo goes. Nocebo is just life.
AlfalFaFail@lemmy.ml â¨2⊠â¨weeks⊠ago
The AMA has a section in their code of ethics about when and how to use a placebo in situations like this.
wonderingwanderer@sopuli.xyz â¨2⊠â¨weeks⊠ago
Thatâs exactly what I was going to say!
âYour cancer is very advanced, and without intervention, you will be dead within the year. Weâre running a clinical trial on an experimental immunotherapy vaccine that can dramatically improve your outcomes. Youâre in the control group, hereâs a placebo.â
sbeak@sopuli.xyz â¨2⊠â¨weeks⊠ago
Itâs important in case the drug that is being tested has unintended side effects, not having a control group means you have no idea if bad things are caused by the drug or by some other external factor (like medical history of the patients, environmentâŚ)
The control group probably isnât given placebo drugs, that probably wouldnât fly in most countries. Havenât looked into these specific trials and Iâm not a medical professional!
CIA_chatbot@lemmy.world â¨2⊠â¨weeks⊠ago
Ironically placebos work so well in almost all cases that placebo results actually screw the data a bit. The human fucking mind is crazy yo
Drusas@fedia.io â¨2⊠â¨weeks⊠ago
Similarly, the nocebo effect also works!