Neuro-biology of trans-sexuality : Prof. Robert Sapolsky

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• chemical_cutthroat@lemmy.world ⁨1⁩ ⁨year⁩ ago

  His latest book Determined is a great read.

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  • benignintervention@lemmy.world ⁨1⁩ ⁨year⁩ ago

    Currently waiting for the audiobook to pop on Libby

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• BrotherL0v3@lemmy.world ⁨1⁩ ⁨year⁩ ago

  This whole class is on YouTube if you search “Stanford human behavioral biology”. Highly recommend it!

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• Fizz@lemmy.nz ⁨1⁩ ⁨year⁩ ago

  Interesting. I was under the impression that the trans brain theory was debunked ages ago.a

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  • foxglove@lazysoci.al ⁨2⁩ ⁨weeks⁩ ago

    not debunked, just made more complicated - gender identity is probably biological, fixed (not subject to social or psychological influences), and the result of the early development of the brain, but … it’s not as clear as a “female brain” and “male brain” like the simple narrative was at first

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  • neuracnu@lemmy.blahaj.zone ⁨1⁩ ⁨year⁩ ago

    I’m not certain whether or not it was effectively debunked, but there’s a lot of personal belief and interest around the idea that one’s gender is what one says it is and no amount of anatomical measurement (genital length, count of brain neurons or genetic flag) is permitted to say whether or not you are what you deem yourself to be.

    If such a test did exist, then what’s to be said of trans people whose gender expression doesn’t line up with the test? What’s to be said of cis people in the same boat? Are they trans whether they like it or not? Are they living a lie?

    It’s a sticky topic either way.

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• Whirling_Cloudburst@lemmy.world ⁨1⁩ ⁨year⁩ ago

  Thanks for the 6min brain tease. Back when I was in school, we didn’t have this information. We were looking for ways to study it. That book he wrote will be a must read.

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• HessiaNerd@lemmy.world ⁨1⁩ ⁨year⁩ ago

  Anybody got a link to the study? Names?

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  • foxglove@lazysoci.al ⁨2⁩ ⁨weeks⁩ ago

    The autopsy studies were done by Dick Swaab, e.g.

    Garcia-Falgueras A, Swaab DF. A sex difference in the hypothalamic uncinate nucleus: relationship to gender identity. Brain. 2008 Dec;131(Pt 12):3132-46. doi: 10.1093/brain/awn276. Epub 2008 Nov 2. PMID: 18980961.

    for a video overview on the science I recommend this overview by Julia Serano: www.youtube.com/watch?v=ZymYiwoRoC0

    This video overview on the variability of sex is also highly recommended: www.youtube.com/watch?v=nVQplt7Chos

    there were some MRI studies by Joel et al. that disrupted the overly simple findings of the autopsy studies:

    Joel D, Berman Z, Tavor I, Wexler N, Gaber O, Stein Y, Shefi N, Pool J, Urchs S, Margulies DS, Liem F, Hänggi J, Jäncke L, Assaf Y. Sex beyond the genitalia: The human brain mosaic. Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15468-73. doi: 10.1073/pnas.1509654112. Epub 2015 Nov 30. PMID: 26621705; PMCID: PMC4687544.

    and for the most up to date article with a collab between Joel & Swaab, I would check-out:

    Joel D, Garcia-Falgueras A, Swaab D. The Complex Relationships between Sex and the Brain. Neuroscientist. 2020 Apr;26(2):156-169. doi: 10.1177/1073858419867298. Epub 2019 Sep 11. PMID: 31509086.

    also worth reading:

    Saraswat A, Weinand JD, Safer JD. Evidence supporting the biologic nature of gender identity. Endocr Pract. 2015 Feb;21(2):199-204. doi: 10.4158/EP14351.RA. PMID: 25667367.

    Korpaisarn S, Safer JD. Etiology of Gender Identity. Endocrinol Metab Clin North Am. 2019 Jun;48(2):323-329. doi: 10.1016/j.ecl.2019.01.002. Epub 2019 Mar 18. PMID: 31027542.

    and finally this meta-analysis on the clinical effects of trans gender-affirming healthcare:

    …cornell.edu/…/what-does-the-scholarly-research-s…

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