foxglove

@foxglove@lazysoci.al

• ⁨Comment⁩ on ⁨Neuro-biology of trans-sexuality : Prof. Robert Sapolsky⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  not debunked, just made more complicated - gender identity is probably biological, fixed (not subject to social or psychological influences), and the result of the early development of the brain, but … it’s not as clear as a “female brain” and “male brain” like the simple narrative was at first

• ⁨Comment⁩ on ⁨Neuro-biology of trans-sexuality : Prof. Robert Sapolsky⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  The autopsy studies were done by Dick Swaab, e.g.

  Garcia-Falgueras A, Swaab DF. A sex difference in the hypothalamic uncinate nucleus: relationship to gender identity. Brain. 2008 Dec;131(Pt 12):3132-46. doi: 10.1093/brain/awn276. Epub 2008 Nov 2. PMID: 18980961.

  for a video overview on the science I recommend this overview by Julia Serano: www.youtube.com/watch?v=ZymYiwoRoC0

  This video overview on the variability of sex is also highly recommended: www.youtube.com/watch?v=nVQplt7Chos

  there were some MRI studies by Joel et al. that disrupted the overly simple findings of the autopsy studies:

  Joel D, Berman Z, Tavor I, Wexler N, Gaber O, Stein Y, Shefi N, Pool J, Urchs S, Margulies DS, Liem F, Hänggi J, Jäncke L, Assaf Y. Sex beyond the genitalia: The human brain mosaic. Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15468-73. doi: 10.1073/pnas.1509654112. Epub 2015 Nov 30. PMID: 26621705; PMCID: PMC4687544.

  and for the most up to date article with a collab between Joel & Swaab, I would check-out:

  Joel D, Garcia-Falgueras A, Swaab D. The Complex Relationships between Sex and the Brain. Neuroscientist. 2020 Apr;26(2):156-169. doi: 10.1177/1073858419867298. Epub 2019 Sep 11. PMID: 31509086.

  also worth reading:

  Saraswat A, Weinand JD, Safer JD. Evidence supporting the biologic nature of gender identity. Endocr Pract. 2015 Feb;21(2):199-204. doi: 10.4158/EP14351.RA. PMID: 25667367.

  Korpaisarn S, Safer JD. Etiology of Gender Identity. Endocrinol Metab Clin North Am. 2019 Jun;48(2):323-329. doi: 10.1016/j.ecl.2019.01.002. Epub 2019 Mar 18. PMID: 31027542.

  and finally this meta-analysis on the clinical effects of trans gender-affirming healthcare:

  …cornell.edu/…/what-does-the-scholarly-research-s…