Comment on I don't get how people can become depressed, when we live in the century of Fentanyl, easy access to alcohol and amusement arcades.

roguetrick@lemmy.world ⁨1⁩ ⁨week⁩ ago

• Swedneck@discuss.tchncs.de ⁨1⁩ ⁨week⁩ ago

  i mean psilocybin (administered by a professional and in a safe environment) is actually documented to work for some people, so maybe hold out for that instead of drugs that may well be 50% drain cleaner depending on where you get it?

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  • cows_are_underrated@feddit.org ⁨1⁩ ⁨week⁩ ago

    MDMA is also documented to be very effective in curing depression, but as you said, its not as easy to tell if they used other stuff to mix it into the MDMA

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    • roguetrick@lemmy.world ⁨1⁩ ⁨week⁩ ago

      Pharmodynamically, it is very similar to how SSRI’s, SNRI’s, and MAOI’s work, just with a much faster time (the aforementioned take about a week). MAOI + MDMA is a surefire way to the bus of serotonin syndrome and cooking yourself from the inside because of that.

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• Mikina@programming.dev ⁨1⁩ ⁨week⁩ ago

  Its what literally changed my life. I was really socialy awkward, spend most of my lide behind a computer, and when I managed to go out to parties in a subculture scene parties I loved, I couldnt talk to anyone, had a few beers awkwardly in a corner and went home.

  Then I met someone who introduced me to MDMA. That happened almost 8 years ago, and now I am an organizer of 2/3 of the same scene regular parties in our city, Im helping and DJing on a festival that happens here, and am living my best life in that regard. All thanks to that one best friend who got me something that made me talk to, and get to actually know people in the scene in the extent that I always wanted, and get comfortable enough that I no longer need to be high to interact with anyone. Since now they are friends and regulars, and not random people I wanted to talk to, but was afraid of approaching.

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  • roguetrick@lemmy.world ⁨1⁩ ⁨week⁩ ago

    For anxiety cases like yours, something that is very seritonigenic (which MDMA is) is very helpful. For unipolar depression without anxiety it may be just a nice manic episode. For bipolar depression, it might be a nice way to get yourself involuntarily committed.

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• AngryPancake@sh.itjust.works ⁨1⁩ ⁨week⁩ ago

  There are amphetamine antidepressants. You can ask your doctor about it (e.g. bupropion, which is not addictive).

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  • roguetrick@lemmy.world ⁨1⁩ ⁨week⁩ ago

    Brother I’ve been on bupropion and I loved it.

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    • AngryPancake@sh.itjust.works ⁨1⁩ ⁨week⁩ ago

      Yeah I’ve been on bupropion for about 1.5 years. Had an increased heart rate in the beginning as well so we started at a very low dosis, then went up step by step. However the side effects vanished after 2 months. I don’t feel hyper active, I just don’t feel super low anymore. It doesn’t make the depression go away but it allows me to work on it, because otherwise I couldn’t even get out of bed

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• UnderpantsWeevil@lemmy.world ⁨1⁩ ⁨week⁩ ago

  the cure for my depression is cocaine or meth

  Adding short bursts of mania to my episodes of depression, because nothing improves my overall mood than a huge rush of endorphins followed by a sharp crash and an aching emptiness.

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  • Crikeste@lemm.ee ⁨1⁩ ⁨week⁩ ago

    Don’t forget the painful regrets of your actions while high!

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• cows_are_underrated@feddit.org ⁨1⁩ ⁨week⁩ ago

  Don’t be a weakling and take MDMA to cure it. Real men learn how to live with your depression /s

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