snoons
@snoons@lemmy.ca
- Comment on [meta] question: who is the person in the sidebar? and why are they there? 2 days ago:
- Comment on [meta] question: who is the person in the sidebar? and why are they there? 2 days ago:
Nah it’s true, I just forgot about it. >.>
- Comment on [meta] question: who is the person in the sidebar? and why are they there? 2 days ago:
I’d rather the image not be removed. Bill Nye is basically the only reason I was able to understand science because most of my teachers didn’t really give a fuck, so they slapped in a Bill Nye tape and called it a day. Seeing his blessed face always fills me with cheer and gratitude.
Well, you can block the image with u-block origin or ad-nauseam.
- Comment on She is so mad she is going to rat you out to jesus 3 days ago:
- Comment on She is so mad she is going to rat you out to jesus 3 days ago:
;-; i suppose. I guess I just don’t want it to be like, all of them you know. like just the existence of their puritanical pr teams has such a deep lasting impact on human culture for memes posted on a small forum to be fucking censored. it pisses me of thinking about and now i want to
make some ppe bmbs or k*ll a ceowork more. - Comment on She is so mad she is going to rat you out to jesus 3 days ago:
I don’t understand where all these corpo boot-licking… no, boot-slobbering memes come from.
- Comment on Looking forward to bikini season 3 days ago:
have some self respect and wear a diaper smh my head
- Comment on Update announcement for the gamers 🚨 4 days ago:
go for a walk
eventually find goldenrod (it’s a flower)
- Comment on It's free real estate 4 days ago:
No no no, first you have to make a subdivision with cookie cutter houses and “whimsical” road planning, then you name it after the mountain ecosystem you bulldozed to make it. The is built at the bottom of the mountain on the less important mountain ecosystem.
- Comment on NSFW post 4 days ago:
I feel that. I hope you meet people that truly care about you, if you haven’t already.
- Comment on Imposed exposure therapy 4 days ago:
Infrared guidance does not count towards optimal experience.
- Comment on SBA #96 THE FOOT LONG COMPENDIUM CONUNDRUM CONCLUDES 4 days ago:
The efficiency of phenylalanine (Phe) utilization for milk protein synthesis in dairy cows is limited, and its uptake and metabolic mechanisms in the mammary tissue remaining unclear. This study investigated the effects of Phe availability (0.07, 0.14, 0.28, and 0.56 mM) on amino acid metabolism and casein synthesis in bovine mammary epithelial cells (BMECs) cultured for 24 h. Results showed that αS1-casein, β-casein, and κ-casein expression peaked at 0.14 mM Phe (p < 0.05). At this optimal concentration, amino acid transporters (SLC7A5, SLC7A8, and SLC38A2) were upregulated, corresponding with enhanced uptake of Met, Ile, His, and Arg (p < 0.05). The mammalian target of rapamycin (mTOR) signaling pathway was activated as evidenced by increased phosphorylation of P70 S6 kinase (P70S6K) and mTOR (p < 0.05), while the general control nonderepressible 2 (GCN2) pathway was suppressed through reduced eukaryotic initiation factor 2α (eIF2α) phosphorylation (p < 0.05). As Phe concentration increased, its net uptake increased linearly (Plinear < 0.05) while uptake efficiency decreased linearly (Plinear < 0.05). High Phe concentration (0.56 mM) inhibited amino acid transporter expression and reduced uptake of Leu, Pro, and Tyr (p < 0.05). Additionally, Phe-to-Tyr conversion was dynamically regulated, with phenylalanine hydroxylase (PAH) activity inhibited at 0.07 mM Phe (p < 0.05) but enhanced at higher concentrations, concurrent with reduced exogenous Tyr uptake (p < 0.05). These findings show that casein synthesis in BMECs is optimal at 0.14 mM Phe, coinciding with enhanced expression of amino acid transporters and activation of protein synthesis pathways. In contrast, higher Phe concentrations (0.56 mM) are associated with reduced amino acid utilization efficiency. These observations suggest potential mechanisms by which Phe concentration may regulate milk protein synthesis in dairy cows.
- Comment on Imposed exposure therapy 4 days ago:
The aliens also want you to take your meds.
- Comment on Doing the Lord's work. 5 days ago:
I kinda thought so, I was referring to the opp.
- Comment on Doing the Lord's work. 6 days ago:
>Posts a meme about being ungovernable.
>Self censors to appease the tech bro corporates - Comment on Don't blink 6 days ago:
I like it when that happens because the hairs scratch itches way back there.
- Comment on Inexplicable 6 days ago:
I prefer the reproductive cycle of hyenas and kangaroos.
- Comment on or rephrasing a sentence til i like how it sounds 1 week ago:
and leaving no room for semantic arguments or arguments in general.
- Comment on Size comparison between eagle talons and a human hand. 1 week ago:
ImageExcuse me?
- Comment on 1 week ago:
- Comment on When the death sticks wear off 1 week ago:
Good boy, Chewbacca.
- Comment on Ancient Proton Calendar prophesies End of World in 2038 1 week ago:
Goddamit. I was about to think about starting to learn how to become immortal and save the universe from it’s entropic demise but it’s pointless now.
- Comment on A/B: Part Duex 1 week ago:
MY first thought was “The front fell off.”
- Comment on Finally, a real name for your penis 1 week ago:
SCHLONG HARD PLEASURE TOOL UNIT
- Comment on anyone know how i can cancel this? I don't want this 1 week ago:
drone strike
blame iran
- Comment on I would watch that ngl 1 week ago:
I’d help too.
- Comment on Apple fail ✂ 1 week ago:
✂️ 🤔
- Comment on Anon teaches you about their culture 1 week ago:
I am angry and sickened at the same time.
- Comment on Anon teaches you about their culture 1 week ago:
Fish n’ chips isn’t complete without it.
- Comment on I use way too many substitute tools. 1 week ago:
Just use some paper towel or something to keep the teeth from fucking shit up and you’re good to go.
