Comment on Protein folding is not solved yet
sharkfucker420@lemmy.ml 6 days agoA reliable way to simulate any kind of protein fold. As long as you have a method you could hypothetically “solve” the issue
Comment on Protein folding is not solved yet
sharkfucker420@lemmy.ml 6 days agoA reliable way to simulate any kind of protein fold. As long as you have a method you could hypothetically “solve” the issue
SaveTheTuaHawk@lemmy.ca 6 days ago
You dont solve anything. You generate models. That’s it. Without experimental validation they are just cartoons.
sharkfucker420@lemmy.ml 6 days ago
Then why has modelling been so focused on?
Hazel@piefed.blahaj.zone 6 days ago
Because the models become a database you can search for certain characteristics.
(This is a guess I consider reasonable.)
Huegoe@fedinsfw.app 6 days ago
Its somewhat complex. Protein structures are usually solved with x-ray crystallography. You get a 2-dimensional diffraction pattern. There are different methods to “solve” tghe diffraction pattern and get the Protein structure. Most are a lot of work, including biochemical lab work. But if you have a model it is relatively easy. The modern computer generated models have revolutionized protein x-ray crystallography.