phdepressed
@phdepressed@sh.itjust.works
- Comment on The Cybertruck Is Not Selling 6 days ago:
Sadly I know at least 3 of these cybershits are in my city.
- Comment on Every damn time. 1 week ago:
Think like a microchip but for cells. These organ on a chip contain various cells to emulate the function and response of an organ.
I recommend finding a different hobby as salt up your urethra sounds unpleasant. But I mean if your partner is into it whatever.
- Comment on Every damn time. 1 week ago:
Yeah, because it’s fast and little pain can be felt before its dead. Guillotines were developed to be a more humane execution for people.
“Physical methods” (Guillotine, cardiac puncture, thoracotomy, etc) are usually a secondary confirmation of death after lethal ketamine/xylazine cocktail injection, isofluorane, or CO2 inhalation.
And yeah we’re sacrificing them to the science god to try and make new discoveries and new therapies. We’re also trying to develop ways to avoid using organisms such as organ on a chip or multiple organ on a chip systems but thats expensive af and not yet sufficient quality to replace organism testing.
- Comment on nothing against that guy, but this was a funny glitch 2 weeks ago:
Lot of reasons behind the replication crisis that basically boil down to two main things. 1) fraud and 2) really miniscule stuff that isn’t practical to consider.
So 1 is pretty self explanatory. 2 for an example can be something as minute as a slight temperature change in what the animal facility is kept at. Or even the time of day animals or cells were treated.
- Comment on Would we be able to use the measles virus to reset the immune systems of people with autoimmune disorders like MS or rheumatoid arthritis? 2 weeks ago:
Aside from some comments mentioning how immune reset therapies are in fact a thing through either antibody or chemical depletion of your immune cells. These can show improvement but it is very far from curative and not too much better chances than existing immune suppression stuff.
The danger to an immune “reset” are that you are generally then able to be reinfected with every cold and flu as well. This is dangerous for older or already fragile people. The existing therapies reduce this danger by not entirely wiping memory cells out but that also means they aren’t always curative.
Beyond that autoimmune diseases in general are a mix of genetics and environmental factors (and even gut bacteria by some studies). If the underlying problem isn’t fixed then relapse is a question of when not if. It’s like adding fluid to a container with a leak, eventually you’re going to have to add more again unless you fix the leak first.
So we have to find where the “leaks” are, what they are caused by and fix the cause(s) to have something that is an actual cure. Right now we mostly know where the leaks are and some causes and can patch some up leaks up. However, we don’t have a way to fix the causes yet and we dont know all of them.
*I am a cell bio PhD but not an immunology specialist.
- Comment on Sup, guise. 2 weeks ago:
No you add DMSO (5-10%) and freeze slowly. Using a Mr frosty or similar. Otherwise a few hours at -20, then -80, before the LN2.
Just chucking in LN2 is going to have terrible recovery. That might have been done with HeLa way back when but certainly isn’t standard anymore.
- Comment on Sup, guise. 2 weeks ago:
I’ve used an enzyme from West Germany. Worked great.
- Comment on Pattern Recognition 3 weeks ago:
I mean its like the top category for the last some years in the US as well. Elon’s dad has multiple children with a woman who was his adopted daughter. The pedo in chief is on TV talking about how attractive his own daughter is. Listening to women and stories of sexual abuse by family are a dime a dozen. I unfortunately don’t think it is just a regional thing but that they are more open with it and don’t take the effects of it seriously.
- Comment on [deleted] 3 weeks ago:
At 22 I didn’t want kids. At 32 I have a kid without regrets. Prior to getting a long-term partner with the same mindset I think it is a bit much unless something or someone has scared you about “baby trapping”.
Vasectomy reversal can usually be done but isn’t always effective.
- Comment on Pattern Recognition 3 weeks ago:
There’s a disturbing trend of pseudo or outright incest in Japanese media. Step siblings, cousins, actual siblings, etc. I mean western porn does it too with step-whatevers but it at least isn’t in kids cartoons afaik.
- Comment on Be nice 3 weeks ago:
Less tracking? Marginally lighter physical wallet? Idk, crypto is a scam as far as I can tell. Sure you can make a whole bunch of money and we’ve decided its legal but its somehow both an investment where you can make and lose millions and a currency to pay for absolutely nothing I’ve ever seen. If there was just one or if a few were based around NAFTA, BRICS or EU whatever it could make sense. But every scummy podcaster and 4chan memer makes their own to scam the participants.
- Comment on New York City commuters could soon start seeing ads for beer and other boozy beverages on subways and buses, ending a seven-year ban by the MTA. 3 weeks ago:
German=good beer. Woman=sex. Drink German beer, have sex, Das Guud tm* (actually just budlight horsepiss in a different bottle).
- Comment on Be nice 3 weeks ago:
That could actually make it a viable currency. Unless you mean the entirety of all bitcoin in which case lol.
- Comment on Inflation Outpaces Wage Growth For Over 40% Of Americans 3 weeks ago:
Yes, billionaires should not exist.
Can we also agree that school should be free and kids should be fed? Can we agree that roads (and rails) should be made and kept safe? Can we agree that our food should be safe to eat and not full of chalk or worse? Etc etc the most practical way to do those things is for everyone to chip in aka taxes.
One of the biggest problems in America is that since Reagan we’ve stopped truly taxing the rich and with that they’ve bought the government or enough of it to write the rules. Removal of the fairness doctrine, the repeal of glass-steagal, and citizens united are three big ones that come to mind. Where one-side can push their view without pushback or seeing the other side the idea of compromise goes out the window. That random opinions started getting treated same as facts is another thing. That companies could do stock buybacks and effectively manipulate their stock prices and C-suite/board pay meaning they can make money even without actual growth. And of course CU where money became speech and companies gained the benefits of being “people” without any of the detriments.
- Comment on Robert F. Kennedy Jr’s explanation for socializing with Jeffrey Epstein 3 weeks ago:
Honestly, that’s pretty much this entire administration.
- Comment on Families took safety into their own hands by painting yellow cross walks. Now, the city of Los Angeles is removing them. 3 weeks ago:
Depending on location there’s additional stuff, mostly signage notifying drivers. With great variation in requirements depending on the road.
- Comment on [deleted] 4 weeks ago:
I can’t speak to it as I haven’t done one but I can get the desire. I never went on a date or had a gf or any sexual experience until I was 25 and it wasn’t for lack of trying…paying for it would be a sort of bandaid to the issue of loneliness but I wonder if it decreases the chance of becoming an incel.
- Comment on [deleted] 4 weeks ago:
If you think about having a gf, there’s a lot more to the relationship than sex. Nonsexual physical intimacy, much less anything emotional is extremely lacking for the average male not in a relationship.
- Comment on It's not just kind, it's kinder 4 weeks ago:
Quite possibly, it was rather popular in my middle school and I think MCR or some other popular band did a music video with them.
- Comment on Itch.io apologise for "frustration and confusion" after delisting thousands of NSFW projects 4 weeks ago:
That’s literally what calling your government representatives is. You’re supposed to be able to pressure your representative to represent you.
- Comment on How much of a persons body is needed to survive? 5 weeks ago:
Yeah, as with most implants there are issues with biofilm/plaques and immunity. They are also not responsive to loading so don’t allow exercise, affect vasculature weirdly etc.
- Comment on How much of a persons body is needed to survive? 5 weeks ago:
Communication only needs the brain nowadays, neuralink is shit but there are options for similar brain-machine interface that are workable for paralyzed people.
Survival is harder. Ecmo, parenteral nutrition, and dialysis are organ supplements not replacements. Lacking lungs, GI, or kidneys will kill you. Dialysis supplements kidney function. Ecmo supplements lungs that are reduced capability. Parenteral nutrition supplements reduced GI function. There are mechanical hearts/assitive devices one dude had a mech heart one for years but you still need blood pumping. The liver has no assitive device you die in 24h without.
- Comment on How come nobody does anything about North Korea? 1 month ago:
Yes, that’s basically what we did in Iraq. It led to a 20y occupation, thousands of troops killed, hundreds of thousands to millions of civilian deaths, and several new terrorist organizations. It will cost the US alone about 8,000,000,000,000. Basically the entirety of cultural progress and then some was lost in a few months.
- Comment on [deleted] 1 month ago:
Perfectly? In a language system different than your own. English to French/Spanish doesn’t require these sounds. English to like Thai or Chinese has a lot.
People learn new languages because you can get the ability back with training (hooray neurplasticity) but it is more difficult and takes longer.
- Comment on [deleted] 1 month ago:
Speaking Japanese honestly isn’t too hard. Reading/writing Japanese is more difficult but is easier as you realize the complex Kanji are just combinations of simpler kanji and how those relate to meaning. Most of the sounds are also in English.
- Comment on Oatmeal 1 month ago:
Mole burrito
- Comment on Can anyone do the maths? 1 month ago:
This decade has lasted centuries.
- Comment on Can it take months to get over being laid off? 1 month ago:
It can take a while to get over a layoff when it’s unexpected, it isn’t so different than a relationship ending. We spend a lot of time at work and often put a lot of ourselves into our jobs.
This could be depression or just delayed grief as needing to find a job on short notice tends to block out a lot of emotion and it can take a bit after getting a job for that block to loosen.
What helps you get out of the funk and what helps someone else get out probably varies. For me a decent walk around the neighborhood/park and decreased phone time are/were very helpful. Even mild alcohol use was a very temporary thing that created a long-term detriment. Society sucks at teaching healthy coping mechanisms.
- Comment on Converting numbers is easy 1 month ago:
This isn’t a question of functionality but just whether a system whether basic arithmetic, music, etc makes logical/intuitive sense.
Imperial measurements using feet, yards, mph, etc instead of metric centimeters, meters, kph, etc. Sure imperial works but it doesn’t make the same sense that metric does. Math can be done in base 2, base 60 or whatever it doesn’t make the same sense as base 10.
- Comment on [deleted] 1 month ago:
It isn’t but if it can’t work at that scale how do you convince anyone it will work when it’s larger scale? Showing feasibility is important.