Oh, I get it! First guy’s answer to the horribly overused meme question “Is it loss?” is to kill second guy, because fuck no, it isn’t loss, goddamit.

Whew! Here I was, worried that it’d actually be that terrible, terrible meme.

Do you really need the spoiler?

The comic clearly references Shia LaBeouf’s Intense Motivational Speech, also known as Just Do It.