If you really want to blow your mind, look into the theoretical alternatives to DNA. we are all taught about RNA and how it is a precursor to DNA, but what if it went another way? Look up PNA, PNA-O, or even GNA. If life existed on other worlds, there is a decent chance it follows an xNA structure, but not necessarily DNA.
Comment on DNAddy
rockSlayer@lemmy.blahaj.zone 5 hours ago
I’m a data analyst at a medical nonprofit, primarily doing analyses on germline variants for rare forms of cancer. I’m new to this kind of work, but had a decent educational background in biology.
Something I’ve learned is that genetics are complicated as hell. A single gene can produce multiple different proteins, and proteins change over time due to somatic variation. Only 1% of the genome are protein coding, called exomes. Exomes can be affected by variations to start and stop codons, non coding regions, and untranslated regions. There are entire fields dedicated to studying genome-wide, exomics, transcriptomics, proteomics, phenomics, and probably several others that I don’t know about. The amount of data involved with these fields is in the tebibytes region. Have you ever seen a “small” 3GiB csv? I have. The filtered and cleaned data frames created by genetics are over 100 columns wide and have nearly 5 million entries.
There are companies creating artificial life by generating custom chromosomes. There’s a whole field of computer science dedicated to biological computing, using DNA as a storage medium. There are companies dedicated to simply classifying genes.
DNA is cool as hell.
MrEff@lemmy.world 4 hours ago
ptu@sopuli.xyz 1 hour ago
Interesting, could you enlighten what types if data is in those 100 columns? I’m aware of ATGC and thought it would be just one column, but maybe the rest are some that indicate intensity or activity. Or what sequence they are part of.
rockSlayer@lemmy.blahaj.zone 1 hour ago
Well it varies depending on what the file is meant for. Usually there’s columns like chromosome, variant position, reference nucleotide, observed nucleotide, type of variation, codon sequence, gene name, etc.
There’s also columns that result from various analyses. In the file I’ve been working on lately, there are columns such as variant impact, level of confidence, pathogenicity, clinical significance, etc.
ptu@sopuli.xyz 55 minutes ago
Sweet, thanks for the reply. I didn’t expect to fully understand what they would contain but I got the idea.
There’s a Japanese artist Ryoji Ikeda who you might like, he has visualised DNA and all sorts of data. I like his data.gram exhibition’s style the most esthetically amusing and he has published some albums too.
homesweethomeMrL@lemmy.world 4 hours ago
That’s too much science. We, as a people, need less sci- wait, no. No, no. Uh - We need bett-er? Science? Hmm.
Look just make it an animated cartoon with fun music for now and we’ll circle back.
pelespirit@sh.itjust.works 5 hours ago
My dude, not a fun thing to think about who might have control over that. Is it a musk, zuck, cook or epstein?
rockSlayer@lemmy.blahaj.zone 5 hours ago
No, none of those guys are involved afaik. The one that made the first breakthrough in artificial life is ran by the same dude who competed with the Human Genome Project to map 99% of the human genome. They modified an extremely simple bacteria that only had something like 300 base pairs
pelespirit@sh.itjust.works 5 hours ago
We still don’t know what type of person they are. Them being smart and focused on the research, doesn’t give them a pass. They could even not care who else has the info.
halcyoncmdr@piefed.social 26 minutes ago
Yup. Many Nazi scientists only cared about the research. A lot of medical and physics breakthroughs last century directly resulted from those experiments.