Comment on Magic Mushrooms Evolved Psilocybin Not Once, but Twice

amos@mander.xyz ⁨4⁩ ⁨days⁩ ago

• prole@lemmy.blahaj.zone ⁨4⁩ ⁨days⁩ ago

  I think reindeer eat them, but I’m not sure if they trip.

  Psilocin is excreted in urine unchanged. I believe native shamans would drink the reindeer’s piss after it had eaten psilocin containing mushrooms that were otherwise inedible to humans.

  I could be misremembering, but I think people would also drink the shaman’s piss after they “filtered” it?

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• idiomaddict@lemmy.world ⁨4⁩ ⁨days⁩ ago

  I’m also super interested in the effects on fungus and psilocybin specifically, but it seems safe to assume that psychoactive compounds can generally affect different organisms differently, given that I’m pretty sure humans would be less capable than the spiders on mescaline and more capable on caffeine (dose dependent, I guess- maybe they just get shaky spinnerets instead of shaky hands).

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  • porcoesphino@mander.xyz ⁨4⁩ ⁨days⁩ ago

    I’d be curious to see that with dosage. Like maybe they’re just more sensitive to caffeine than originally expected, kind of how humans were way more sensitive to LSD than expected. But also, the effects of LSD in humans seem to plateau unlike alcohol, it would be interesting to see if the caffeine web is the spider falling off a metaphorical cliff

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    • idiomaddict@lemmy.world ⁨4⁩ ⁨days⁩ ago

      I think your instinct is right and invertebrates might be more affected by caffeine, because I did a lab on how fruit fly larvae respond to caffeine in which about a third of the class inadvertently killed their larvae.

      I also suspect humans are less likely to continue trying fine motor tasks if they’re close to dangerously overdosing on caffeine, because it’s unpleasant as hell and most people would probably seek out medical attention instead of knitting through it.

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