Comment on Seek relief
Sheeple@lemmy.world 7 months ago
Excuse me I would rather not build up resistance to painkillers and then be screwed once I REALLY need painkillers.
The headache sucks, but it’s not wisdom tooth level pain
So much medical misinformation in this thread but it looks like there’s some merit to acetaminophen tolerance.
Less so NSAIDs. They definitely need more studies that take human populations into account because there aren’t any I could find that weren’t in rats.
Regarding acetaminophen resistance: pubmed.ncbi.nlm.nih.gov/18468992/
Less so NSAIDs.
Not sure why you were downvoted, this a quality comment with academic sources.
Because the people using Lemmy are no better than the people using Reddit lol.
AKA my personal experience always beats science. Even if it’s placebo or nocebo. Also unless you’ve already beat that vote threshold when initially posting, it’s hard to turn it back. And if you’re posting something contrarian to what’s already upvoted despite it being misleading or false, then chances are whoever’s agreeing are going to be reading it more than the people disagreeing.
In circumstances like there, there are some very rare cases that don’t apply to 99.999% of the population, but it DOES apply to them. Biology be fucked like that. However you could never have a conversation on the internet if all you did was cite exceptions or anticipate personal anecdotes lol.
enki@lemm.ee 7 months ago
There’s a VERY big difference between “pain relievers”, NSAIDs, and “pain killers” which are opioids. NSAIDs are effective and safe if used properly.
Zagorath@aussie.zone 7 months ago
Not all pain killers fit into those two categories.
The normal headache pill, paracetamol (most notably sold as “Panadol”), is neither NSAID nor opioid.
I_Fart_Glitter@lemmy.world 7 months ago
That’s Tylenol (acetaminophen) for the US folks.
Zagorath@aussie.zone 7 months ago
Oh yeah, that’s right. That’s a weird one. Not sure why they have two such different names.
enki@lemm.ee 7 months ago
Your distinction is correct, but I simply listed NSAIDs as an example, not an exhaustive list of pain relievers. You also make assumptions on “the normal headache pill” based on your locale. In the US paracetamol/acetaminophen/Tylenol is very common, but so is ibuprofen/Advil, naproxen sodium/Aleve, and aspirin/Bayer. In fact, I’d argue ibuprofen is far more popular here based on how much larger the ibuprofen section is compared to acetaminophen in pharmacies. Granted acetaminophen is a bit more common in compound OTC meds like cold and flu medicines.
That being said, paracetamol functions extremely similarly to NSAIDs, but it’s not anti-inflammatory, and works on the nervous system only, whereas NSAIDs affect the brain and body as well.