Hmm… F.I.S.T: Forged in Shadow Torch is ~50 hour-ish—metroidvania with great combat.

Catherine is +100 hours if you go for 100%. Fantastic puzzle game.

Maybe check out Okami if you're into Zelda-likes.

Vanquish is probably the coolest 3rd-person shooter out there.

Signalis is one of the best survival horror indies.

Lastly, Prey if you're looking for more immersive sims.