It depends on the book.

One of my favorite books is Good Omens (obligatory fuck Neil Gaiman). I have multiple print copies of various editions. I have multiple digital copies. The digital copies all suck because the footnotes, which are arguably the best parts of the book, are always at the end of the book rather than at the bottom of the pages. I also love to read Good Omens by picking up a copy, opening to a random page, and begin reading there.

I also read a lot of TTRPG books, I read digital copies in bed on my iPad. For actual game I always prefer a physical copy.