AnyOldName3

@AnyOldName3@lemmy.world

• ⁨Comment⁩ on ⁨Childhood trauma 😩⁩ ⁨⁨3⁩ ⁨days⁩ ago⁩:

  It never went away. They just figured out how to make it subtle so it could be active all the time instead of just when the computer wasn’t working properly. Do you really feel like you’re using trauma-free software day-to-day?

• ⁨Comment⁩ on ⁨Should speakers hum when they're connected to a stereo, but the volume of is turned all the way down?⁩ ⁨⁨1⁩ ⁨week⁩ ago⁩:

  If the ferrite is filtering a hum you can hear, it’s also filtering parts of your music that you can hear because a ferrite just dampens a frequency range and can’t tell what is and isn’t supposed to be there.

• ⁨Comment⁩ on ⁨Get on that grindset⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  And the context was a sentence that was correct if you used OED sense 1, or MW sense 1, but you decided to parse it as MW sense 2b and then complain that the sentence was incorrect.

• ⁨Comment⁩ on ⁨Will the government be able to put 2 & 2 together⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  Obviously they’ll have a carve-out for businesses that apply for a VPN licence and have the other end of the VPN remain in the country. Not because they listen to the public saying that VPNs have legitimate uses, but because the megacorp they consult with before drafting the law says it’s the only legitimate use-case and has a VPN product they can sell to small businesses that can’t afford to wait for their self-hosted VPN to be certified by the one overworked civil servant who has sole responsibility for approving every VPN licence.

• ⁨Comment⁩ on ⁨Get on that grindset⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  OED:

  1. totally or partially resistant to a particular infectious disease or pathogen.
  2. protected or exempt, especially from an obligation or the effects of something.

  Merriam Webster

  1. : not susceptible or responsive especially: having a high degree of resistance to a disease
  2. a: produced by, involved in, or concerned with immunity or an immune response

  If you have a sample of HIV at 37°C in blood, but with all the immune cells removed, it’ll still all become inert after around a week simply due to chemical reactions with other components of blood etc… It’s pretty comparable to a population of animals - if you take away their ability to reproduce, they’ll die of old age when left for long enough even if you’re not actively killing them.

• ⁨Comment⁩ on ⁨Get on that grindset⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:
  • this is a shitpost community, not a biotech publication, so immune here means the dictionary definition, not any domain-specific technical jargon, otherwise people can’t make shitposts about diplomatic immunity
  • lacking the receptor that HIV uses to hijack the regular immune response in order to reproduce means the regular immune response destroys it
  • even in a normal person, after exposure, a lot of HIV gets destroyed by other parts of the immune system, often enough to eliminate it before an infection gains a foothold. Once an infection takes hold, it outbreeds the immune response as it’s the part best equipped to deal with a large viral load that it interferes with.
  • if you’ve got the virus in your body, but due to the lack of the receptor, it can’t reproduce, then it doesn’t remain viable for very long as each viron accumulates damage over time, and ceases to function once it’s too badly damaged. People carrying a disease have enough viral reproduction going on to balance out the virus being destroyed.
• ⁨Comment⁩ on ⁨Get on that grindset⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  Even if you ignore that there’s an entirely valid sense of the word immune that has nothing do do with biology (i.e. the one in phrases like diplomatic immunity), my original comment is entirely consistent with the dictionary definition of the biological sense of the word. There are probably sub-fields of biology where immunity is used as jargon for something much more specific than the dictionary definition, but this is lemmyshitpost, not a peer-reviewed domain-specific publication.

• ⁨Comment⁩ on ⁨Get on that grindset⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  When a normal person is exposed to HIV, it reproduces inside of them, so can then go on to expose more people, and if there’s enough of it, infect them in turn (if there’s a smaller amount, their immune system will normally be able to clean it up before it gets enough of a foothold). If someone’s lacking the receptor, then no matter how much they were exposed to, their immune system will eventually manage to remove it all without becoming infected because it can’t reproduce. If they had a ludicrously large viral load, then there’s a possibility that it could be passed on before it was destroyed, but most of the ways people get exposed to HIV aren’t enough to infect someone who’s vulnerable, let alone infect someone else via secondary exposure if there’s not been time for the infection to grow.

• ⁨Comment⁩ on ⁨Get on that grindset⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  People without the receptor that HIV targets are immune to HIV because of that, like how a rock is immune to verbal abuse or double foot amputees are immune to ingrown toenails. The immune system being able to kill something isn’t the only way things can be immune to other things.

• ⁨Comment⁩ on ⁨Get on that grindset⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  That tests the AIDS immunity, but not whether there are off-target edits. IIRC, the mothers were all HIV-positive, so the children are all pretty likely to be exposed anyway, which was part of how he justified the experiment to himself.

• ⁨Comment⁩ on ⁨Get on that grindset⁩ ⁨⁨2⁩ ⁨weeks⁩ ago⁩:

  If he got incredibly lucky, they’re immune to AIDS. It’s much more likely that they’re not and will develop symptoms of new and exciting genetic disorders never seen before.

  The biggest problem was that the technique used is really unreliable, so you’d expect off-target edits to be more common than on-target ones for a human-sized genome. For bacteria, you can get around it by letting the modified bacteria reproduce for a few generations, then testing most of them. If they’re all good, then it worked, and if any aren’t, you need to make a new batch. Testing DNA destroys the cells you’re testing, so if you test enough cells in a human embryo to be sure that the edits worked, it dies. You can’t just start when the embryo is a single cell to ensure that the whole thing’s been edited in the same way as you need to test something pre-edit to be able to detect off-target edits.

• ⁨Comment⁩ on ⁨Teenage Jehovah's Witness can receive blood transfusion, judge rules⁩ ⁨⁨4⁩ ⁨weeks⁩ ago⁩:

  In the UK, if there’s a medical issue with any legal or ethical ambiguity, especially if a child is involved, doctors are required to defer the decision to a court. It means a lot of decisions end up being made by courts.

• ⁨Comment⁩ on ⁨Day 517 of posting a Daily Screenshot from the games I've been playing⁩ ⁨⁨5⁩ ⁨weeks⁩ ago⁩:

  Obviously, most people don’t replace their TV every year, so it was years after new sales were mostly LCDs that most people had LCDs, but companies making content like to be sure it looks good with the latest screens.

• ⁨Comment⁩ on ⁨Day 517 of posting a Daily Screenshot from the games I've been playing⁩ ⁨⁨5⁩ ⁨weeks⁩ ago⁩:

  I think you might have misjudged when LCDs became common as by the end of 2004, when Halo 2 released, LCD TVs were already a reasonable fraction of new TV sales, and in parts of the world, it was only a few months later that LCD TVs became the majority. For PC monitors, the switch came earlier, so it was clear CRTs were on the way out while the game was being developed. If they hadn’t expected a significant number of players to use an LCD and tweaked the game as much as necessary to ensure that was fine, it would have been foolish

• ⁨Comment⁩ on ⁨for a better future for ur children⁩ ⁨⁨1⁩ ⁨month⁩ ago⁩:

  There have been times it’s been used against a whole carful of people, and cars are bigger than seven inches.

• ⁨Comment⁩ on ⁨same shit every day, on god⁩ ⁨⁨1⁩ ⁨month⁩ ago⁩:

  It’ll heat up the firebox, which is exactly what the firebox wants to happen. It’s not like we’re using precisely-timed explosives to briefly make the mass much more than critical and counter its desire to blow itself apart for long enough that it blows other things apart, too.

• ⁨Comment⁩ on ⁨same shit every day, on god⁩ ⁨⁨1⁩ ⁨month⁩ ago⁩:

  You can boost it by hollowing out the middle and filling it with tritium, but plutonium is dense, so 80 tons will probably fit in the firebox just fine.

• ⁨Comment⁩ on ⁨Standardization rule⁩ ⁨⁨1⁩ ⁨month⁩ ago⁩:

  In a lot of the world they’re regulated as novelty items, so free from the regulation that stops harmful chemicals being in things like kitchen utensils and childrens’ toys, despite many of the same potential risks being present. You don’t need to use a corner-cutting regulation-ignoring retailer like Wish to get your fix of toxic plasticisers etc…

• ⁨Comment⁩ on ⁨OnLy tWo eLemEnTs⁩ ⁨⁨1⁩ ⁨month⁩ ago⁩:

  You get both sizes of gametes with all kinds of bodies. It’s only the testes/ovaries that are reliably correlated with gamete size, and anything further away from their production than that has about the same chance of not being the style you’d expect as an atom has of not being hydrogen or helium, just like the original meme alludes to.

• ⁨Comment⁩ on ⁨⁩ ⁨⁨1⁩ ⁨month⁩ ago⁩:

  As it says in the article, it’ll be smaller and quieter, so less offensive for most people’s living rooms than a full-size desktop. It’s not meant to replace your existing PC if you have one, unless it was getting old and you were about to replace it anyway. If you don’t have a PC, or don’t have one in the living room, then it might be a better option than anyone else’s prebuilt.

• ⁨Comment⁩ on ⁨Had to look this up⁩ ⁨⁨2⁩ ⁨months⁩ ago⁩:

  It tends to attract negative attention if you admit there’s a civil war going on.

• ⁨Comment⁩ on ⁨Learner driver fails theory test for 128th time despite spending nearly £3k on fees⁩ ⁨⁨2⁩ ⁨months⁩ ago⁩:

  No, but if he hadn’t been bullied by people who’d passed when he told them he’d failed and interrogated about what on Earth he could have done to fail, it would probably have taken him more tries than it did.

• ⁨Comment⁩ on ⁨Learner driver fails theory test for 128th time despite spending nearly £3k on fees⁩ ⁨⁨2⁩ ⁨months⁩ ago⁩:

  Some of them don’t exactly replicate the hazard perception part. My brother misunderstood and thought you were supposed to spam click as fast as possible for the whole duration of each hazard, which worked just fine on his practice website, but got him instafailed for too many clicks on the real thing.

• ⁨Comment⁩ on ⁨Global Warming [Photographic Evidence]⁩ ⁨⁨2⁩ ⁨months⁩ ago⁩:

  It’s probably more risqué than that - with the rise of cam sites and then OnlyFans, plenty of people aren’t wearing any underwear at their day job at all.

• ⁨Comment⁩ on ⁨snail lyfe⁩ ⁨⁨2⁩ ⁨months⁩ ago⁩:

  It’s 2025. Even snails are renting their homes these days.

• ⁨Comment⁩ on ⁨You dont have to answer silly questions⁩ ⁨⁨2⁩ ⁨months⁩ ago⁩:

  These days, the majority of users refuse to use anything except discord, unless they’re willing to leap further into the abyss and ask an LLM. Forums end up dead, with very few users asking anything, and no one except devs coming back regularly to answer questions, so they still end up with devs dealing with every question themselves.

• ⁨Comment⁩ on ⁨The Steam Controller's stick is upgradeable!⁩ ⁨⁨3⁩ ⁨months⁩ ago⁩:

  I’m not sure I’d consider this a total upgrade - I have a Steam Controller and an 8bitdo SN30 Pro, and despite the 8bitdo one being newer and having been used much less, I wore through its original thumbstick rubber and had to replace it much sooner than the Steam Controller’s thumbstick cap, which hasn’t even worn through, it was just flaking.

  Either that was a fluke, or the 8bitdo rubber isn’t as durable.

• ⁨Comment⁩ on ⁨'Buy one, get one free' deals for unhealthy food banned in supermarkets⁩ ⁨⁨3⁩ ⁨months⁩ ago⁩:

  Unless you’re a Ferengi or Ayn Rand, a free market shouldn’t allow agents within the market to manipulate each other, as that inhibits trades being done solely based on what gives the best value for the least currency, making the market less free. The regulation here isn’t taking away a choice you want to have as supermarkets that run BOGOF offers just set the unit price to the cost of two units, so your choice is between paying for two things and getting two things or paying for two things and only getting one. Effectively, your choice to just buy one thing at a fair price is taken away by supermarkets, and it’s dressed up to make it look like you’re getting a bargain when you pay a fair price for two things and get two things.

  A parenthood licence is a really common trope in dystopian fiction because it’s fundamentally the most authoritarian thing a state could do short of mind control. If you don’t trust a government to decide whether or not there should be BOGOF offers on crisps, you absolutely shouldn’t trust them to decide who gets to have children. For most of the twentieth century, the British government was actively trying to suppress minority political opinions like it being acceptable for people to be homosexual or anti-pollution. If they’d been deciding what the requirements were to get a parenthood licence, they’d absolutely have made people agree to teach their children that it wasn’t okay to be gay etc…

• ⁨Comment⁩ on ⁨'Buy one, get one free' deals for unhealthy food banned in supermarkets⁩ ⁨⁨3⁩ ⁨months⁩ ago⁩:

  Unless you want to do something dystopian like requiring a parenthood licence before people are allowed to have children and then force them to keep it renewed by attending regular parenthood classes, you can’t force people to receive education on how to be better parents. The state doesn’t have many levers to pull that don’t involve taking people’s children away. Making harmful products less appealing by preventing retailers promoting them is a much better balance of good effect against oppression. The kind of deal being restricted here is something supermarkets do because it manipulates people into buying things they otherwise wouldn’t. It’s not like every time you see a BOGOF sale in a shop it’s because they’re overstocked and are trying to clear things before they go past their sell-by date. If that’s not happening, then the only rational reason for supermarkets to have these deals is to manipulate their customers, and it’s not oppressive for a government to prevent multi-billion pound companies from manipulating its citizens.

• ⁨Comment⁩ on ⁨'Buy one, get one free' deals for unhealthy food banned in supermarkets⁩ ⁨⁨3⁩ ⁨months⁩ ago⁩:

  You can have loyalty cards from as many shops as you want, so it’s not inherently anti-competitive. They’re not even particularly meant to encourage loyalty, they’re a way to track what individuals buy over multiple trips and then deliver targeted advertising. The non-loyalty-card prices are high to ensure that customers are incentivised to sign away their data.