Gene regulatory network - Clock and Flip-flop

Comments

• appel@whiskers.bim.boats ⁨9⁩ ⁨months⁩ ago

  This is pretty cool, but is there a reason to use NN rather than differential equations? Seems like it might be more computationally expensive.

  Are you using some kind of declarative language to define the networks? Not sure if a standard for that exists yet. There are the standard symbols for genetic circuits though.

  source

  • sixfold@lemmy.sdf.org ⁨9⁩ ⁨months⁩ ago

    Well, it is technically differential equations, but with weighted inputs like a NN. Here’s the equations

    Image

    Image

    Image

    for each node (gene/morphogen) i. f(x) is the sigmoid function, k1 is the maximum rate of expression, k2 is the degradation rate, b is the bias. wij is the weight for an edge from j to i.

    What are the standard symbols for genetic circuits?

    source