No, you need an audio interface such as a Signalink or Digirig.

You could also make a simple interface with a couple of audio cables connected to your sound card. You will need an L pad to reduce the line level from the computer down to microphone level for the radio. For some modes like SSTV, you can use the VOX function on your radio to transmit, Many other modes will need some sort of PTT control because VOX will be too slow.