Comment on Joe 3:16
TranscendentalEmpire@lemm.ee 2 weeks agoI mean, coke is basically an amphetamine with a shittier half life. They’re both stimulants with a dopamine re-uptake inhibitors.
Coke is just the shittier and less ethically sourced option.
Laser@feddit.org 2 weeks ago
That’s not how amphetamine works. It’s correct for cocaine, but amphetamine promotes dopamine release, it doesn’t inhibit reuptake.
In the end, both increase dopamine availability… but through different mechanisms and they’re chemically different as well.
TranscendentalEmpire@lemm.ee 2 weeks ago
Amphetamines are also DRI…
“The following are a selection of some particularly notably abused DRIs: cocaine, ketamine, MDPV, naphyrone, and phencyclidine (PCP). Amphetamines, including amphetamine, methamphetamine, MDMA, cathinone, methcathinone, mephedrone, and methylone, are all DRIs as well, but are distinct in that they also behave, potentially more potently, as dopamine releasing agents (DRAs)”
Amphetamines are dopamine releasing agents, but they also affect dopamine re-uptake.