Good point about our perception of reality. If we have drugs available to us that can make us perceive reality as not that bad (or even good), then what if it’s just a defect in our bodies that makes us feel like life isn’t worth living? If our bodies are simply defective in producing the mood balancing hormones, then depression or other mood disorders can be treated with medicines, no different than taking a Tums when we overindulge on Thanksgiving.