I have a similar experience when I go a city in my state - St. Paul. If I go downtown for any reason, I always feel a bit uneasy walking about and I didn’t know why for the longest time. I finally found out that the streets in the downtown aren’t laid out on the cardinal points-- They were laid out on a slight bias due to being right up against the Mississippi river. And that makes me a little uncomfortable when looking down a block of buildings or from one street to the next at an intersection. It’s always a little bit wonky feeling.