If it’s homemade (including the sauce) on thin crust of proper bread dough (again, homemade) and you’re generous and careful with the toppings (avoiding salty and/or highly processed stuff), the only inherently imbalanced thing is the cheese (which is excessive for something that high in saturated fats).

Then again, homemade pizza done from scratch including the sauce and the bread dough takes more than an hour to make, so people overwhelmingly buy pizza already make (or at least ready to bake), and then it’s loaded crap because you really can’t trust industrial food.