Besides basic housekeeping machinery, different cells are very different, especially when talking about their metabolism.

Adiposites are practically dead, as they have very little metabolism, while liver and brains are very active, muscles too when being used. skin has very little metabolism, and the epidermis (outer skin layer) has absolutely no metabolism.

I could talk more, got a cell biology degree and a phd in genomics. but I’m at the ivory throne and don’t want my legs to stop their metabolism due to the seat stopping the blood flow.