One retro game that I think hasn’t really been well-imitated since is called The Last Express. You’re on the last major express train through Europe before World War I.

What sets it apart is both a very vivid art style using rotoscoping of live actors, as well as a real-time gameplay system wherein the NPCs of the train can constantly move around, scoot past you in the car hallways, or even seek you out during certain key events.