geekwithsoul

@geekwithsoul@piefed.social

• ⁨Comment⁩ on ⁨For the first time since COVID, more than half of Fortune 100 companies have mandated workers fully return to work as hybrid options wither⁩ ⁨⁨2⁩ ⁨days⁩ ago⁩:

  City governments have been pushing hard because they're worried about their tax base and economies - not so much for the office space itself (though that's in danger), but the ancillary businesses like coffee shops, lunch places, and car parks. It's a shitty reason, as they could take the opportunity to rearchitect office space into livable housing and solve the problem that way - but they don't want to.

• ⁨Comment⁩ on ⁨What do you call the first person with a new genetic mutation⁩ ⁨⁨1⁩ ⁨week⁩ ago⁩:

  Such changes are called germ-line mutations because they occur in a cell used in reproduction (germ cell), giving the change a chance to become more numerous over time. If the mutation has a deleterious affect on the phenotype of the offspring, the mutation is referred to as a genetic disorder. Alternately, if the mutation has a positive affect on the fitness of the offspring, it is called an adaptation. [Nature]

  I'm assuming you mean "mutation that gets passed down". Whether a mutation is a disorder or an adaptation takes generations to determine, so we may not know the identity of the individual. Furthermore, what was once a disorder may become adaptive in a different environment and vice versa. In general, I suppose if it was adaptive, they might be called "ancestor" :)

  More broadly, and outside of germ-line mutations (meaning it's not passed down to offspring), everyone has cells with mutations. The person doesn't have the mutation per se, but a cell or cluster of cells do, so identifying them by that mutation doesn't make a lot of sense. If it's bad, your body either kills it or it kills you (e.g. cancer). If it's good, it likely doesn't change anything significantly.