In short, yes, but it has to be carefully controlled, and on your terms.

I have adhd, I regularly take medication for it. It has a significant effect on my personality. I takes away the “excited labrador puppy” energy, which is replaced with a more calm and considerate version of me.

It’s worth noting that this change is something I wanted. The improvements for others is a nice side benefit. It’s also done with medical supervision.

It’s also worth noting that the change does become more permanent. Even when unmedicated, I can mode switch far more easily than before. My brain understands the new state better and so can recreate it, even without chemical support.