Comment on Miracle cures
ForgotAboutDre@lemmy.world 6 months agoThis study is absolutely terrible.
The study found no differences in the first four weeks. More than 10% dropped out during the study. The study was too small a sample to draw any serious conclusions from. The conclusions they did draw from were a subsample of people they declared treatment resistant. They even say in the paper their isn’t enough data to suggest their was any benefit, just not forcefully enough. Just enough to make low information readers think the study was successful.
This study was done in response to two other studies. One which showed no benefit another that suggested a benefit, but the study lacked a control group. So no meaningful conclusion could be drawn.
Finally the researchers were funded by ‘health supplement’ groups.
canihasaccount@lemmy.world 6 months ago
I’m not saying the study is good, just that the meme isn’t true.
Also, you can level almost every single one of those criticisms against many studies for SSRIs and they’d hit just as hard. The exception being sample size.
ForgotAboutDre@lemmy.world 6 months ago
The evidence is much better for SSRI, and it isn’t great, but the referred paper even points out that the curriculum wasn’t as effective as an SSRI.
The meme remains true, no proper or valid studies exist. The existence of a paper doesn’t prove that, the paper is self addresses it wasn’t a proper study. They just did it in a dishonest way.
canihasaccount@lemmy.world 6 months ago
Why are you completely ignoring the second paper I linked, which doesn’t suffer from any of the limitations you mentioned?
The meme says no trial was successful. Any trial with any small difference is a successful trial.
ForgotAboutDre@lemmy.world 6 months ago
I didnt bother reading the second since the first was blatantly misleading.
The second looks like they’re trying to p hack hack their way to a result.
They also have more relapses in the curicumin group in the second 6 month period than the control group. They also have enough people leaving the control group to cause a shift in their p value to make their results insignificant.
The second papers findings are weak and they aren’t very robust.