I think that the Nazis or Japanese did experiments in that vain, but don’t quote me on it. They did quite a lot that makes my stomach roil. As to how far they could get, no clue.

Either way, once organs start to be removed, you won’t be around for long. Under most circumstances anyways. We do have the ability to sub in machines for failed organs, such as heart, kidneys or lungs, but I don’t know of any cases where all of them have been replaced with machines at the same time with the “patient” still awake during.

Full life support tends to be a “Buddy, your fucked!” sort of thing and if you’re not already in a coma, they will likely put you in one.