It really depends on a handful of things. For context, I’m in northern Ontario.

I’m an introvert, and I spend most of my time alone. I thrive by myself, so being alone (for a while) won’t be an issue. However, I would bet over time I might lose my mind with zero presence of people.

Farming is possible, but the area isn’t great. Most of my food would be from hunting and fishing, which I do already.

I’m also surrounded by lots of fresh water, so that is not a concern. My house is heated by a mix of propain and wood, so heating in the winter is not an issue.

Winter’s will be tough, because roads won’t be plowed. Eventually fuel will go bad and I won’t have any running vehicle, including snowmobiles. So I would likely be walking with snow shoes, or staying inside. This would then require me to stock up all my food, which is its own issue.

Electrical grid would likely go down. If I want to preserve my food using freezers before the winter, I will need electricity, which would require me.installing some sort of solar system. I’m not knowledgeable on the subject, which would require me to go physically searching for books or written documentation.

Electricity is paramount for any future long distance travel, as combustion engines would not be operable, and electric vehicles would replace them.

Moving south to a warmer climate where hunting/fishing is still possible, and surrounded by fresh water would probably be best.

Long story short, loneliness would likely kill me before anything else does.