As you’re using the terms being thrown around lately, I’ll assume you just spit out what you hear without actual knowledge. There is no such thing as biological man or woman. There are sexes but even that isn’t binary, it’s a spectrum with many outliers that have sex disorders. Additionally, chromosomes does not equal phenotype. There are men out there with XX and women with a Y chromosome. Additionally, sex characteristics and phenotype are not just based on chromosomes; it is complex and varied. Trans people have the same variations as cis people, but their brains exhibit similar traits as their cis counterparts, while being in a body that exhibits similar sex characteristics as those on the opposing end of the spectrum. This is where the misalignment and dysphoria comes from. I’m obviously making something far more complex simplified.