I kidt had a problem with my boss’s conouter yesterday where Windows decided it didn’t need to load the drivers for one of the two built in USB 3.0 controllers. On boot, only one of the two controllers would work, either the one for the front ports, or the one for the rear ports.

BIOS recognized a keyboard or mouse in any of the 2.0 or 3.0 ports at POST, but if Windows failed to load the 3.0 driver at boot time, it dropped the keyboard and mouse.

Workaround was to swap them to the 2.0 ports. Final solution was upgrading to Linux.