Titanfall 2 is one of the greatest games of all time (I would say it is easily a top 50, maybe even a top 20). The singleplayer campaign is just ridiculously well designed and even has a surprising amount of pathos in the narrative.

But if you are likely to be regularly interrupted? Horizon Zero Dawn. most of the story quests are 10-15 minutes each and you can just do the checklist open world the rest of the time.